4|-Demethylepipodophyllotoxin

CAS No. 6559-91-7

4|-Demethylepipodophyllotoxin( —— )

Catalog No. M15493 CAS No. 6559-91-7

A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 30 Get Quote
50MG 42 Get Quote
100MG 54 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    4|-Demethylepipodophyllotoxin
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
  • Description
    A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    TopoII
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    6559-91-7
  • Formula Weight
    400.3787
  • Molecular Formula
    C21H20O8
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C1OC[C@]2([H])[C@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(O)C(OC)=C5)[C@]21[H]
  • Chemical Name
    Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-,(5R,5aR,8aR,9S)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dhawan D, et al. Carcinogenesis. 1999 Jun;20(6):997-1003. 2. Gewirtz DA. Cancer Res. 1985 Dec;45(12 Pt 1):6290-2. 3. Lee KH, et al. J Med Chem. 1990 May;33(5):1364-8.
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